3-Chloro-1-propanol → 1-(3-Chloro-propoxymethyl)-3-fluoro-2-methoxy-benzene

HRID 1838751Notes

Reaction equation

HRID 1838751 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][OH:5].Cl[CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([F:14])[C:9]=1[O:15][CH3:16]>>[Cl:1][CH2:2][CH2:3][CH2:4][O:5][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([F:14])[C:9]=1[O:15][CH3:16]

Participants

3

Reactant 2

HCID 123133-Chloro-1-propanolHCID 225059631-(Chloromethyl)-3-fluoro-2-methoxybenzene

Product 1

HCID 187554011-(3-Chloro-propoxymethyl)-3-fluoro-2-methoxy-benzene

Procedure

In an analogous manner to that described in (δ) 1-chloromethyl-3-fluoro-2-methoxy-benzene was reacted with 1-chloro-3-propanol to yield 1-(3-chloro-propoxymethyl)-3-fluoro-2-methoxy-benzene as a colorless liquid; MS: 232 (M)+.

Sources & evidence

ORD record
ord-34fa25fb16e142caaedee77facefa8e6
Source dataset
uspto-grants-2004_01
Patent number
US06673931B2

Reaction notes

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