HCID 20820309, compound → HCID 22344765, compound

Participants

Reaction Steps

1.4 g of tert-butyl-(5-tert-butoxycarbonylmethyl-2,6-dioxoperhydro-1,5-diazocin-1-yl)acetate (starting material A3) are dissolved in 6 ml of dichloromethane and admixed with 6 ml of trifluoroacefic acid. The mixture is stirred overnight and then concentrated using a rotary evaporator, and the residue is triturated with ethyl acetate/petroleum ether (1:1). The residue is filtered off with suction and dried under reduced pressure. This gives 0.89 g of the title compound of m.p. from 250° C. (decomposition). The mass spectrum shows the molecular peaks MH+ and MNH4+ at 259 and 276 Da.

Provenance & Evidence