HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl trifluoroacetate → 2-N-trifluoroacetyl-6-N-benzyloxycarbonyl-lysine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl trifluoroacetate | HCID 9794 | — |
| Reactant | epsilon-(Benzyloxycarbonyl)-L-lysine | HCID 1715626 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-N-trifluoroacetyl-6-N-benzyloxycarbonyl-lysine | HCID 86585333 | — |
Reaction Steps
100 g (356.7 mmol) of 6-N-benzyloxycarbonyl-lysine is dissolved in a mixture that consists of 1000 ml of trifluoroacetic acid ethyl ester/500 ml of ethanol, and it is stirred for 24 hours at room temperature. It is evaporated to the dry state, and the residue is crystallized from diisopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06676928B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-88995d39a6bc432bbd33073b252a1ed7 |
| Source note | uspto-grants-2004_01 |