4-Phenylbutyric Acid → HCID 10200608, compound

HRID 1838931Notes

Reaction equation

HRID 1838931 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[O:30])[CH2:11][N:12]1[CH2:17][CH2:16][N:15]([C:18](=[O:29])[CH:19](O)[CH2:20][CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:14][CH2:13]1.C1(CCCC(O)=O)C=CC=CC=1.OC1C=CC=CC=1[C@@H](CC)C(O)=O>>[CH3:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([CH3:1])[C:3]=1[NH:9][C:10](=[O:30])[CH2:11][N:12]1[CH2:17][CH2:16][N:15]([C:18](=[O:29])[CH2:19][CH2:20][CH2:21][C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH2:14][CH2:13]1

Participants

4

Reactant 3

HCID 47754-Phenylbutyric AcidHCID 12985297HCID 12985297, compoundHCID 69892093HCID 69892093, compound

Product 1

HCID 10200608HCID 10200608, compound

Procedure

Compound 13 was prepared in the manner of compound 7 substituting 4-phenylbutanoic acid for (R)-2-hydroxy-phenylbutyric acid in part C to afford compound 13: Mass spectrum (M+1) =394.40.

Sources & evidence

ORD record
ord-d18ae036a837476dab5cc4c198f4112e
Source dataset
uspto-grants-2004_01
Patent number
US06677343B2

Reaction notes

Loading…