HCID 12985297, compound → HCID 12985298, compound

HRID 1838935Notes

Reaction equation

HRID 1838935 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[O:30])[CH2:11][N:12]1[CH2:17][CH2:16][N:15]([C:18](=[O:29])[CH:19]([OH:28])[CH2:20][CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:14][CH2:13]1.OC1C=CC=CC=1[C@@H](CC)C(O)=O>>[OH:28][C@H:19]([CH2:20][CH2:21][C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)[C:18]([N:15]1[CH2:14][CH2:13][N:12]([CH2:11][C:10]([NH:9][C:3]2[C:4]([CH3:8])=[CH:5][CH:6]=[CH:7][C:2]=2[CH3:1])=[O:30])[CH2:17][CH2:16]1)=[O:29]

Participants

3

Reactant 2

HCID 12985297HCID 12985297, compoundHCID 69892093HCID 69892093, compound

Product 1

HCID 12985298HCID 12985298, compound

Procedure

Compound 18 was prepared in the manner of compound 7 substituting R-2-hydroxy-4-phenylbutyric acid for (R)-2-hydroxy-phenylbutyric acid in part C to afford compound 18. Mass spectrum (M+1)=410.44.

Sources & evidence

ORD record
ord-1daaf2dc523e43dca8ad2b17ca11f10a
Source dataset
uspto-grants-2004_01
Patent number
US06677343B2

Reaction notes

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