1-(Methanesulfonyl)piperidin-4-amine → [2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(2,6-difluoro-phenyl)-methanone

HRID 183915Notes

Reaction equation

HRID 183915 reaction equation
[CH3:19][S:20](=[O:21])(=[O:22])[N:23]1[CH2:24][CH2:25][CH:26]([NH2:29])[CH2:27][CH2:28]1.[NH2:1][c:2]1[n:3][c:4]([Cl:18])[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([F:17])[cH:12][cH:13][cH:14][c:15]1[F:16]>>[NH2:1][c:2]1[n:3][c:4]([NH:29][CH:26]2[CH2:25][CH2:24][N:23]([S:20]([CH3:19])(=[O:21])=[O:22])[CH2:28][CH2:27]2)[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([F:17])[cH:12][cH:13][cH:14][c:15]1[F:16]

Participants

3

Reactant 2

HCID 113558261-(Methanesulfonyl)piperidin-4-amineHCID 58590833(2-Amino-6-chloro-pyridin-3-yl)-(2,6-difluoro-phenyl)-methanone

Product 1

HCID 11690063[2-Amino-6-(1-methanesulfonyl-piperidin-4-ylamino)-pyridin-3-yl]-(2,6-difluoro-phenyl)-methanone

Sources & evidence

ORD record
ord-1c4fb897e8ec4aecb70c15d3f3a47923
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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