3-Cyanobenzoyl chloride → HCID 23450334, compound

HRID 1839465Notes

Reaction equation

HRID 1839465 reaction equation
[CH3:1][O:2][C:3]1[CH:17]=[CH:16][C:6]([O:7][CH2:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[NH2:11])=[CH:5][CH:4]=1.[C:18]([C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][CH:28]=1)[C:23](Cl)=[O:24])#[N:19]>>[C:18]([C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][CH:28]=1)[C:23]([NH:11][C:10]1[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=1[CH2:8][O:7][C:6]1[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:17][CH:16]=1)=[O:24])#[N:19]

Participants

3

Reactant 2

HCID 3084833-Cyanobenzoyl chlorideHCID 23450361HCID 23450361, compound

Product 1

HCID 23450334HCID 23450334, compound

Procedure

Using a procedure similar to Example 1B except starting from 2-[(4-methoxyphenoxy)methyl]aniline and 3-cyanobenzoyl chloride, the title compound was obtained as a solid (0.50 g, 36%); MS(FD): 359.

Sources & evidence

ORD record
ord-02ac07a8453c4ec58195117318d55f30
Source dataset
uspto-grants-2004_01
Patent number
US06677369B2

Reaction notes

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