Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Benzoyl-L-asparagine → (2S)-6-[[(2S)-4-amino-2-benzamido-4-oxo-butanoyl]amino]-2-[isobutyl(p-tolylsulfonyl)amino]hexanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Benzoyl-L-asparagine | HCID 7062826 | — |
| 반응물 | Nalpha-isobutyl-Nalpha-(4-methylbenzenesulfonyl)-L-lysine | HCID 23552860 | — |
| 생성물 | (2S)-6-[[(2S)-4-amino-2-benzamido-4-oxo-butanoyl]amino]-2-[isobutyl(p-tolylsulfonyl)amino]hexanoic acid | HCID 508586 | — |
반응 단계
The title compound was prepared from Nα-isobutyl-Nα-(4-methylbenzenesulfonyl)-L-lysine (100 mg, 0.29 mmol, example 1, step E) as described in general procedure Bc using Nα-benzoyl-L-asparagine (70 mg, 0.3 mmol) which was prepared in step A this example. The final product was purified by preparative HPLC to yield 14 mg (9%) of the desired material.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06677367B2 |
| 출처 데이터셋 | uspto-grants-2004_01 |
| ORD ID | ord-27b2713f5d0e4174a029e03ffef3ab72 |
| 출처 메모 | uspto-grants-2004_01 |