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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1839645Generated: October 30, 2026

1-Methylpiperazine → 3-methyl-4-(4-methyl-piperazine-carbonyl)-1H-pyrrole-2-carbaldehyde

https://huagongshe.com/reaction/1839645

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant5-Formyl-4-methyl-1H-pyrrole-3-carboxylic acidHCID 22135453—
Product3-methyl-4-(4-methyl-piperazine-carbonyl)-1H-pyrrole-2-carbaldehydeHCID 22390955—

Reaction Steps

5-Formyl-4-methyl-1H-pyrrole-3-carboxylic acid (500 mg, 3.27 mmol) reacted with 1-methylpiperazine (0.43 mL, 3.92 mmol) to give 3-methyl-4-(4-methyl-piperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06677368B2
Source datasetuspto-grants-2004_01
ORD IDord-4dafa77fbcab41d0ab063d1136681b4e
Source noteuspto-grants-2004_01