反应详情

To a stirred solution of 1,5,6,7-tetrahydro-indol-4-one (5.4 g) in pyridine (40 mL) was added hydroxyammonium chloride (2 eq.) at rt. After 2 hours, the solvent was removed and the residue was diluted with water and extracted with ethyl acetate. The combined extracts were washed with brine, dried and concentrated to give 5.5 g of 1,5,6,7-tetrahydro-indol-4-one oxime as a pale yellow solid.

1. customthe solvent was removed
2. additionthe residue was diluted with water
3. extractionextracted with ethyl acetate
4. washThe combined extracts were washed with brine
5. customdried
6. concentrationconcentrated