HCID 22135440, compound → HCID 60061390, compound

HRID 1839811Notes

Reaction equation

HRID 1839811 reaction equation
[O:1]=[C:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[C:11]2[CH:12]=[C:13]([CH2:17][C:18]([OH:20])=[O:19])[CH:14]=[CH:15][CH:16]=2)[NH:3]1.[CH3:21][C:22]1[C:26]([C:27]([N:29]2[CH2:34][CH2:33][O:32][CH2:31][CH2:30]2)=[O:28])=[CH:25][NH:24][C:23]=1[CH:35]=O>C(O)C>[CH3:21][C:22]1[C:26]([C:27]([N:29]2[CH2:30][CH2:31][O:32][CH2:33][CH2:34]2)=[O:28])=[CH:25][NH:24][C:23]=1/[CH:35]=[C:10]1\[C:2](=[O:1])[NH:3][C:4]2[C:9]\1=[C:8]([C:11]1[CH:12]=[C:13]([CH2:17][C:18]([OH:20])=[O:19])[CH:14]=[CH:15][CH:16]=1)[CH:7]=[CH:6][CH:5]=2

Participants

4

Reactant 2

HCID 22135440HCID 22135440, compoundHCID 22561828HCID 22561828, compound

Product 1

HCID 60061390HCID 60061390, compoundYield 53.2%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

[3-(2-Oxo-2,3-dihydro-1H-indol-4-yl)-phenyl]-acetic acid (80.1 mg, 0.3 mmol) was condensed with 3-methyl-4-(morpholine-4-carbonyl)-1H-pyrrole-2-carbaldehyde (66.7 mg, 0.3 mmol) in ethanol to give 75.3 mg of the titled compound.

Sources & evidence

ORD record
ord-7af5913c8d7a4b8f99f92a3694b7bbc2
Source dataset
uspto-grants-2004_01
Patent number
US06677368B2

Reaction notes

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