HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → HCID 60061539, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | HCID 22561714 | HCID 22561714 | — |
| Reactant | HCID 91556839 | HCID 91556839 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 60061539 | HCID 60061539 | 60% |
Reaction Steps
4-(2,4-Difluoro-phenyl)-1,3-dihydro-indol-2-one (73.5 mg, 0.3 mmol) was condensed with 2-formyl-5-methyl-1H-pyrrole-3-carboxylic acid (2-hydroxy-3-pyrrolidin-1-yl-propyl)-amide (excess) and piperidine in ethanol to give 75 mg (60%) of the titled compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06677368B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-5068da785cf84a99977283127f128863 |
| Source note | uspto-grants-2004_01 |