HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-Fluoro-phenyl)-1,3-dihydro-indol-2-one → HCID 60061549, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-Fluoro-phenyl)-1,3-dihydro-indol-2-one | HCID 22561756 | — |
| Reactant | HCID 22561924 | HCID 22561924 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 60061549 | HCID 60061549 | — |
Reaction Steps
4-(2-Pyrrolidin-1-yl-ethyl)-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (0.2 was condensed with 4-(3-fluoro-phenyl)-1,3-dihydro-indol-2-one (0.2 mmol) and piperidine (2 drops) in ethanol at rt for overnight. The solvent was removed and the residue was purified on a silica gel column to give 25 mg of the titled compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06677368B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-791ef12846354ad299d705e064fe8402 |
| Source note | uspto-grants-2004_01 |