Methylamine hydrochloride → HCID 23447734, compound

HRID 1840273Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH:23]([CH3:25])[CH3:24])[C:11](=[O:26])[C:10]=2[C:27]([OH:29])=O)=[CH:5][CH:4]=1.Cl.[CH3:31][NH2:32]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[C:14]([C:15]3[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=3)=[N:13][N:12]([CH:23]([CH3:25])[CH3:24])[C:11](=[O:26])[C:10]=2[C:27](=[O:29])[NH:32][CH3:31])=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 6364545Methylamine hydrochloride

HCID 23447725HCID 23447725, compound

Product 1

HCID 23447734HCID 23447734, compoundYield 92.3%

Procedure

Using 5,6-bis(4-methoxyphenyl)-4-carboxy-2-isopropyl-2H-pyridazin-3-one and methylamine hydrochloride as starting materials, the procedures of Example 22 were repeated likewise, whereby the title compound was obtained in a yield of 92.3%.

Sources & evidence

ORD record: ord-dd00191356de409c8b0bf3b2c5364b5b
Source dataset: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06680316B1

Reaction notes

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