Methylamine hydrochloride → HCID 23447726, compound

HRID 1840275Notes

Reaction equation

HRID 1840275 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH2:23][CH:24]3[CH2:26][CH2:25]3)[C:11](=[O:27])[C:10]=2[C:28]([OH:30])=O)=[CH:5][CH:4]=1.Cl.[CH3:32][NH2:33]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH2:23][CH:24]3[CH2:26][CH2:25]3)[C:11](=[O:27])[C:10]=2[C:28](=[O:30])[NH:33][CH3:32])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 6364545Methylamine hydrochlorideHCID 12114197HCID 12114197, compound

Product 1

HCID 23447726HCID 23447726, compoundYield 88.2%

Procedure

Using 5,6-bis(4-methoxyphenyl)-4-carboxy-2-cyclopropylmethyl-2H-pyridazin-3-one and methylamine hydrochloride as starting materials, the procedures of Example 22 were repeated likewise, whereby the title compound was obtained in a yield of 88.2%.

Sources & evidence

ORD record
ord-3e750808708d44f59d340911bd15fbe6
Source dataset
uspto-grants-2004_01
Patent number
US06680316B1

Reaction notes

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