2-Pyridinemethanamine → HCID 23447718, compound

HRID 1840277Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH2:23][CH:24]3[CH2:26][CH2:25]3)[C:11](=[O:27])[C:10]=2[C:28]([OH:30])=O)=[CH:5][CH:4]=1.[NH2:31][CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][N:34]=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=3)=[N:13][N:12]([CH2:23][CH:24]3[CH2:25][CH2:26]3)[C:11](=[O:27])[C:10]=2[C:28](=[O:30])[NH:31][CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][N:34]=2)=[CH:5][CH:4]=1

Participants

Reactant 2

HCID 195092-Pyridinemethanamine

HCID 12114197HCID 12114197, compound

Product 1

HCID 23447718HCID 23447718, compound

Procedure

Using 5,6-bis(4-methoxyphenyl)-4-carboxy-2-cyclopropylmethyl-2H-pyridazin-3-one and 2-(aminomethyl)pyridine as starting materials, the procedures of Example 22 were repeated likewise, whereby the title compound was obtained quantitatively.

Sources & evidence

ORD record: ord-c85a58b48f2f47c6baeb5aaa109978f6
Source dataset: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06680316B1

Reaction notes

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