Methylamine hydrochloride → HCID 23447719, compound

HRID 1840279Notes

Reaction equation

[CH2:1]([N:8]1[C:13](=[O:14])[C:12]([C:15](O)=[O:16])=[C:11]([C:18]2[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=2)[C:10]([C:26]2[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[CH:28][CH:27]=2)=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH3:35][NH2:36]>>[CH2:1]([N:8]1[C:13](=[O:14])[C:12]([C:15](=[O:16])[NH:36][CH3:35])=[C:11]([C:18]2[CH:19]=[CH:20][C:21]([O:24][CH3:25])=[CH:22][CH:23]=2)[C:10]([C:26]2[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[CH:28][CH:27]=2)=[N:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 6364545Methylamine hydrochloride

HCID 23447728HCID 23447728, compound

Product 1

HCID 23447719HCID 23447719, compoundYield 90.9%

Procedure

Using 2-benzyl-5,6-bis(4-methoxyphenyl)-4-carboxy-2H-pyridazin-3-one and methylamine hydrochloride as starting materials, the procedures of Example 22 were repeated likewise, whereby the title compound was obtained in a yield of 90.9%.

Sources & evidence

ORD record: ord-e9310d37c2ba4e67b024aac52c7ba697
Source dataset: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06680316B1

Reaction notes

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