HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 3-Phenyl-5-(3-phenylpropyl)isoxazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 3-Phenyl-5-(2-phenylethyl)isoxazole-4-carboxylic acid | HCID 23447906 | — |
| Product | 3-Phenyl-5-(3-phenylpropyl)isoxazole-4-carboxylic acid | HCID 23447887 | 72% |
Reaction Steps
The title compound was prepared as described for Compound 28A but substituting 2-phenylethylbromide for benzyl bromide. The crude was purified by flash chromatography (ethyl acetate-petroleum ether-acetic acid 1:1:0.01 mL) to afford the title compound (72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06680319B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-168ab362c36b44b29c13146257c680bf |
| Source note | uspto-grants-2004_01 |