HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 131724300, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Reactant | Phenylthiourea | HCID 676454 | — |
| Reactant | HCID 131724301 | HCID 131724301 | — |
| Product | HCID 131724300 | HCID 131724300 | 49.3% |
Reaction Steps
Following the general procedure for protected phenyl thiourea formation outlined in example 1, N-(2,3-dichlorophenyl)-N′-[4-chloro-2-hydroxy-3-(N″-tetrahydroisoxazylaminosulfonyl)phenyl]thiourea (898 mg, 1.81 mmol), tert-butyldimethylsilyl chloride (1.4 g, 9.05 mmol) and imidazole (246 mg, 3.62 mmol) were reacted to form the desired product (546 mg, 49%). EI-MS m/z 611.81 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06680317B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-c2b2e855adf347549ec9b08aebbe2887 |
| Source note | uspto-grants-2004_01 |