Triethylamine → HCID 131724302, compound

Participants

Reaction Steps

Following the general procedure for carbodiimide formation outlined in example 1, N-(2-bromophenyl)-N′-[4-chloro-2-tert-butyldimethylsilyloxy-3-(N″-tetrahydroisoxazylaminosulfonyl)phenyl]thiourea (385 mg, 0.74 mmol), methanesulfonyl chloride (0.12 mL, 1.48 mmol) and triethylamine (0.21 mL, 1.48 mmol) were reacted to form the desired product (385 mg, crude). 1H NMR (CDCl3) δ 0.35 (s, 6H), 1.02 (s, 9H), 1.68 (m, 2H), 1.9 (m, 2H), 3.04 (t, 2H), 4.0 (t, 2H), 7.09 (d, 1H), 7.12 (d, 1H), 7.2 (d, 1H), 7.3 (t, 1H), 7.42 (d, 1H), 7.6 (d, 1H).

Provenance & Evidence