Triethylamine → HCID 131724303, compound

Participants

Reaction Steps

Following the general procedure for carbodiimide formation outlined in example 1, N-(2,3-dichlorophenyl)-N′-[4-chloro-2-tert-butyldimethylsilyloxy-3-(N″-tetrahydroisoxazylaminosulfonyl)phenyl]thiourea (547 mg, 0.897 mmol), methanesulfonyl chloride (0.14 mL, 1.79 mmol) and triethylamine (0.25 mL, 1.79 mmol) were reacted to form the desired product (547 mg, crude). 1H NMR (CDCl3) δ 0.36 (s, 6H), 1.03 (s, 9H), 1.68 (m, 2H), 1.9 (m, 2H), 3.53 (t, 2H), 4.0 (t, 2H), 7.11 (m, 2H), 7.14 (t, 1H), 7.2 (d, 1H), 7.3 (d, 1H), 7.39 (d, 1H).

Provenance & Evidence