Triethylamine → HCID 23447743, compound

Participants

Reaction Steps

Following the general procedure for carbodiimide formation outlined in example 12, N-(2-chlorophenyl)-N′-[4-chloro-2-tert-butyldimethylsilyloxy-3-(N″,N″-dimethylaminosulfonyl)phenyl]thiourea (311 mg, 0.58 mmol), methanesulfonyl chloride (0.09 mL, 1.16 mmol) and triethylamine (0.15 mL, 1.16 mmol) were reacted to form the desired product (300 mg, crude). 1H NMR (CDCl3) δ 0.37 (s, 6H), 1.03 (s, 9H), 2.87 (s, 6H), 7.05 (d, 1H), 7.12 (t, 1H), 7.22 (m, 2H), 7.34 (d, 1H), 7.42 (d, 1H).

Provenance & Evidence