HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → HCID 23447801, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 1,2-difluoro-3-isothiocyanatobenzene | HCID 2758330 | — |
| Reactant | N,N-Dimethyl-3-amino-6-chloro-2-hydroxybenzenesulfonamide | HCID 23447758 | — |
| Product | HCID 23447801 | HCID 23447801 | 55.3% |
Reaction Steps
Following the general procedure for thiourea formation outlined in example 12, N,N-dimethyl-3-amino-6-chloro-2-hydroxybenzenesulfonamide (500 mg, 2 mmol) and 2,3-difluorophenylisothiocyanate (342 mg, 2 mmol) were coupled to form the desired thiourea (467 mg, 54%). EI-MS m/z 422.2 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06680317B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-45f04ecd6e5c4eb79a6fafb2613cd31c |
| Source note | uspto-grants-2004_01 |