反应详情

Following the general procedure for thiourea formation outlined in example 12, N,N-dimethyl-3-amino-6-chloro-2-hydroxybenzenesulfonamide (526 mg, 2.10 mmol) and 2-chloro-4-fluorophenylisothiocyanate (586 mg, 3.1 mmol) were coupled to form the desired thiourea (505 mg, 55%). EI-MS m/z 437.75 (M−).