反应详情

This compound was prepared from toluene-4-sulfonic acid 3-methoxy-4-methyl-7-oxo-7H-5,10-diaza-benzo[c]fluoren-6-yl ester (Example 18c-1) and 1-(2-aminoethyl)pyrrolidine in a similar manner to Example 18d. The desired product was obtained as a reddish powder. ESI−MS: m/z 389 (MH+); 1H-NMR (CDCl3): δ1.86 (4H, m), 2.50 (3H, s), 2.72 (4H, m), 2.90 (2H, t, J=6.5 Hz), 3.89 (2H, quartet like, J=ca 6.5 Hz), 4.02 (3H, s), 7.12 (1H, d, J=9 Hz), 7.18 (1H, brt, J=ca 5 Hz), 7.54 (1H, dd, J=4.5 Hz, 1 Hz), 8.04 (1H, d, J=9 Hz), 8.80 (1H, d, J=4.5 Hz), 9.27 (1H, brs).