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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1840464Generated: October 30, 2026

p-nitrobenzyl (1R,3R,5R,6S)-6-[(R)-1-hydroxyethyl]-2-oxo-1-methylcarbapenam-3-carboxylate → HCID 90946805, compound

https://huagongshe.com/reaction/1840464

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-nitrobenzyl (1R,3R,5R,6S)-6-[(R)-1-hydroxyethyl]-2-oxo-1-methylcarbapenam-3-carboxylateHCID 13504349—
ReactantHCID 22631827HCID 22631827—
ProductHCID 90946805HCID 9094680511.3%

Reaction Steps

The procedure of Example 1a) was repeated, except that 807 mg of 4-nitrobenzyl (1R,3R,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-oxo-1-carbapenam-3-carboxylate and 1.255 g of 7-(pyridin-2-yl)methylthio-2-(tri-n-butylstannyl)imidazo[5,1-b]thiazole were used as the starting compounds. Thus, 149 mg of 4-nitrobenzyl (1S,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-[7-(pyridin-2-yl)methylthioimidazo[5,1-b]thiazol-2-yl]-1-carbapen-2-em-3-carboxylate was prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06680313B2
Source datasetuspto-grants-2004_01
ORD IDord-0e23e3daa844400f909339ac47f55d07
Source noteuspto-grants-2004_01