HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-nitrobenzyl (1R,3R,5R,6S)-6-[(R)-1-hydroxyethyl]-2-oxo-1-methylcarbapenam-3-carboxylate → HCID 90946805, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-nitrobenzyl (1R,3R,5R,6S)-6-[(R)-1-hydroxyethyl]-2-oxo-1-methylcarbapenam-3-carboxylate | HCID 13504349 | — |
| Reactant | HCID 22631827 | HCID 22631827 | — |
| Product | HCID 90946805 | HCID 90946805 | 11.3% |
Reaction Steps
The procedure of Example 1a) was repeated, except that 807 mg of 4-nitrobenzyl (1R,3R,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-oxo-1-carbapenam-3-carboxylate and 1.255 g of 7-(pyridin-2-yl)methylthio-2-(tri-n-butylstannyl)imidazo[5,1-b]thiazole were used as the starting compounds. Thus, 149 mg of 4-nitrobenzyl (1S,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-[7-(pyridin-2-yl)methylthioimidazo[5,1-b]thiazol-2-yl]-1-carbapen-2-em-3-carboxylate was prepared.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06680313B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-0e23e3daa844400f909339ac47f55d07 |
| Source note | uspto-grants-2004_01 |