Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1840470Generated: October 31, 2026

p-nitrobenzyl (1R,3R,5R,6S)-6-[(R)-1-hydroxyethyl]-2-oxo-1-methylcarbapenam-3-carboxylate → HCID 91538965, compound

https://huagongshe.com/reaction/1840470

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-nitrobenzyl (1R,3R,5R,6S)-6-[(R)-1-hydroxyethyl]-2-oxo-1-methylcarbapenam-3-carboxylateHCID 13504349—
ReactantHCID 23447676HCID 23447676—
ProductHCID 91538965HCID 9153896555.1%

Reaction Steps

The procedure of Example 1a) was repeated, except that 503 mg of 4-nitrobenzyl (1R,3R,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-oxo-1-carbapenam-3-carboxylate and 808 mg of 7-(pyridin-4-yl)sulfonyl-2-(tri-n-butylstannyl)imidazo[5,1-b]thiazole were used as the starting compounds. Thus, 466 mg of 4-nitrobenzyl (1S,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-[7-(pyridin-4-yl)sulfonylimidazo[5,1-b]thiazol-2-yl]-1-carbapen-2-em-3-carboxylate was prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06680313B2
Source datasetuspto-grants-2004_01
ORD IDord-f6c6ed28ff50435d8135eb7582dfde5a
Source noteuspto-grants-2004_01