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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1840552Generated: October 30, 2026

HCID 54450914, compound → HCID 54029713, compound

https://huagongshe.com/reaction/1840552

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54450914HCID 54450914—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 54029713HCID 5402971384.3%

Reaction Steps

A solution of 1-(1-acetyl-4-methoxycarbonylpiperidin-4-ylmethyl)-4-benzyloxycarbonyl-2-oxo-1,2,3,4-tetrahydropyrazine (2.4 g) and 10% palladium on carbon (500 mg) in methanol (100 ml) was stirred at room temperature for 15 hours, under hydrogen atmosphere, and the catalyst was filtered off. The reaction solution was concentrated to give colorless oil of the title compound (1.40 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06680312B2
Source datasetuspto-grants-2004_01
ORD IDord-04a1a12448154328963cf44bc5434ea1
Source noteuspto-grants-2004_01