HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(7-chloro-2H-benzopyran-3-sulfonyl)-1-[1-(4-pyridyl)piperidin-4-ylmethyl]-2-piperazinone Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-(7-chloro-2H-benzopyran-3-sulfonyl)-1-[1-(4-pyridyl)piperidin-4-ylmethyl]-2-piperazinone | HCID 23447364 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-(7-chloro-2H-benzopyran-3-sulfonyl)-1-[1-(4-pyridyl)piperidin-4-ylmethyl]-2-piperazinone Hydrochloride | HCID 23447438 | 147.2% |
Reaction Steps
To the obtained 4-(7-chloro-2H-benzopyran-3-sulfonyl)-1-[1-(4-pyridyl)piperidin-4-ylmethyl]-2-piperazinone (608 mg) was added a solution of hydrochloric acid in ethyl acetate to give colorless solid of the title compound (480 mg) as hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06680312B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-e1029ccca9404efbb1fcf4eeccdf07b2 |
| Source note | uspto-grants-2004_01 |