HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 184060Generated: October 31, 2026
1,4-Dioxane → N-Cyclopropyl-6-[3-(3,4-difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinamide
https://huagongshe.com/reaction/184060
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | Trimethylaluminum | HCID 16682925 | — |
| Reactant | 6-[3-(3,4-Difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester | HCID 66718164 | — |
| Product | N-Cyclopropyl-6-[3-(3,4-difluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinamide | HCID 46928969 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
|---|
| ORD ID | ord-8ff12aa01e9e4351aeea670bfe25d84b |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
|---|
