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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1840663Generated: October 31, 2026

Piperine → Tetrahydropiperine

https://huagongshe.com/reaction/1840663

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperineHCID 638024—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductTetrahydropiperineHCID 58167678.5%

Reaction Steps

Piperine (2 g, 7 mmol) was hydrogenated in ethanol (50 ml) over 5% Pd—C under a pressure of hydrogen at 10 psi for 30 mins to give tetrahydropiperine (1.59 g, 78% yield) as an oil2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06680391B2
Source datasetuspto-grants-2004_01
ORD IDord-ba11e7bffb1549a1afdcb62974ffff8d
Source noteuspto-grants-2004_01