HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(1,3-Benzodioxol-5-yl)prop-2-enoic acid → 3-(Benzodioxol-5-yl)propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(1,3-Benzodioxol-5-yl)prop-2-enoic acid | HCID 16917 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(Benzodioxol-5-yl)propionic acid | HCID 64810 | 82.6% |
Reaction Steps
3-benzo-1,3-dioxol-5-ylacrylic acid (2 g) was hydrogenated in ethanol (50 ml) over 5% Pd—C under a pressure of hydrogen at 10 psi for 40 mins to give 3-benzo-1,3-dioxol-5-ylpropionic acid (1.67 g, 80% yield) as a solid, m.p. 86.1°-88.3° C. (Lit m.p. 87-88° C.)10
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06680391B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-815f0fc615844e2baa22ed4e37dd5958 |
| Source note | uspto-grants-2004_01 |