Benzene → Phenol

HRID 1840672Notes

Reaction equation

HRID 1840672 reaction equation
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:8]1[CH:13]=CC=C[CH:9]=1.C=CC>CC(C)=O>[CH:8]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)([CH3:13])[CH3:9].[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

6

Reactant 3

HCID 241BenzeneHCID 996PhenolHCID 8252Propylene

Product 2

HCID 996PhenolHCID 7406Cumene

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

In industry, phenol is normally prepared by means of benzene alkylation with propylene to give isopropyl benzene, oxidation to the corresponding tert-hydroperoxide and subsequent cleavage to phenol and acetone in the presence of an acid catalyst.

Sources & evidence

ORD record
ord-b8bb01f42a9947d28dfd1c0d6f0f0c39
Source dataset
uspto-grants-2004_01
Patent number
US06680413B2

Reaction notes

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