6-Acetyl-4,4-dimethyl-1-octyl-3,4-dihydroquinolin-2(1H)-one → HCID 69890388, compound

HRID 1840880Notes

Reaction equation

HRID 1840880 reaction equation
[CH2:1]([N:7]1[C:16]2[C:11](=[CH:12][C:13]([C:17](=[O:29])[CH:18]=[CH:19][C:20]3[CH:28]=[CH:27][C:23]([C:24]([OH:26])=[O:25])=[CH:22][CH:21]=3)=[CH:14][CH:15]=2)[C:10]([CH3:31])([CH3:30])[CH2:9][C:8]1=[O:32])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH2:33](N1C2C(=CC(C(=O)C)=CC=2)C(C)(C)CC1=O)[CH2:34]CCCCCC>>[CH2:1]([N:7]1[C:16]2[C:11](=[CH:12][C:13]([C:17](=[O:29])[CH:18]=[CH:19][C:20]3[CH:28]=[CH:27][C:23]([C:24]([OH:26])=[O:25])=[CH:22][CH:21]=3)=[CH:14][CH:15]=2)[C:10]([CH3:31])([CH3:30])[CH2:9][C:8]1=[O:32])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:33][CH3:34]

Participants

3

Reactant 2

HCID 234447046-Acetyl-4,4-dimethyl-1-octyl-3,4-dihydroquinolin-2(1H)-one2×HCID 69891371HCID 69891371, compound

Product 1

HCID 69890388HCID 69890388, compoundYield 24%

Procedure

Following a procedure similar to that used for the preparation of Compound 8a but using N-octyl-6-acetyl-4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one (Intermediate 6c) as starting material afforded the title compound as a light yellow solid (24% yield).

Sources & evidence

ORD record
ord-a015f7306fb640b7bdee7c909d6ddb3c
Source dataset
uspto-grants-2004_01
Patent number
US06683092B1

Reaction notes

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