Phenylpropiolic Acid → HCID 20613746, compound

HRID 1840884Notes

Reaction equation

HRID 1840884 reaction equation
Cl.Cl.[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[C@@H:5]([NH2:11])[CH2:4]2.[C:12]1([C:18]#[C:19][C:20](O)=[O:21])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[C@@H:5]([NH:11][C:20](=[O:21])[C:19]#[C:18][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH2:4]2

Participants

3

Reactant 2

HCID 69475Phenylpropiolic AcidHCID 12494972(R)-(+)-3-Aminoquinuclidine Dihydrochloride

Product 1

HCID 20613746HCID 20613746, compound

Procedure

Prepared as a free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and 3-phenylpropynoic acid; MS (ES+) 255 (MH+).

Workup

  1. customPrepared as a free base by a method analogous to

Sources & evidence

ORD record
ord-672f90d5c07e4cbea16d7b5121396c76
Source dataset
uspto-grants-2004_01
Patent number
US06683090B1

Reaction notes

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