alpha-Fluorocinnamic acid → HCID 20613767, compound

HRID 1840888Notes

Reaction equation

HRID 1840888 reaction equation
Cl.Cl.[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[C@@H:5]([NH2:11])[CH2:4]2.[F:12]/[C:13](=[CH:17]\[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)/[C:14](O)=[O:15]>>[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[C@@H:5]([NH:11][C:14](=[O:15])/[C:13](/[F:12])=[CH:17]/[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)[CH2:4]2

Participants

3

Reactant 2

HCID 1550911alpha-Fluorocinnamic acidHCID 12494972(R)-(+)-3-Aminoquinuclidine Dihydrochloride

Product 1

HCID 20613767HCID 20613767, compound

Procedure

Prepared as free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and Z-2-fluoro-3-phenylpropenoic acid; MS (ES+) 275 (MH+).

Workup

  1. customPrepared as free base by a method analogous to

Sources & evidence

ORD record
ord-e942f890b150406b8875353633cc4fb6
Source dataset
uspto-grants-2004_01
Patent number
US06683090B1

Reaction notes

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