(2E)-3-(4-nitrophenyl)prop-2-enoic acid → HCID 20613763, compound

HRID 1840890Notes

Reaction equation

HRID 1840890 reaction equation
Cl.Cl.[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[C@@H:5]([NH2:11])[CH2:4]2.[N+:12]([C:15]1[CH:20]=[CH:19][C:18](/[CH:21]=[CH:22]/[C:23](O)=[O:24])=[CH:17][CH:16]=1)([O-:14])=[O:13]>>[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[C@@H:5]([NH:11][C:23](=[O:24])/[CH:22]=[CH:21]/[C:18]1[CH:17]=[CH:16][C:15]([N+:12]([O-:14])=[O:13])=[CH:20][CH:19]=1)[CH2:4]2

Participants

3

Reactant 2

HCID 737157(2E)-3-(4-nitrophenyl)prop-2-enoic acidHCID 12494972(R)-(+)-3-Aminoquinuclidine Dihydrochloride

Product 1

HCID 20613763HCID 20613763, compound

Procedure

Prepared as free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-3-(4-nitrophenyl)propenoic acid; MS (ES+) 302 (MH+).

Workup

  1. customPrepared as free base by a method analogous to

Sources & evidence

ORD record
ord-bf9df6d835e14124ab1e2ce1b7bbab5c
Source dataset
uspto-grants-2004_01
Patent number
US06683090B1

Reaction notes

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