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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1840895Generated: October 25, 2026

alpha-Phenylcinnamic acid, (E)- → (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(E-2,3-diphenylpropenamide)

https://huagongshe.com/reaction/1840895

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Phenylcinnamic acid, (E)-HCID 700620—
Reactant(R)-(+)-3-Aminoquinuclidine DihydrochlorideHCID 12494972—
Product(R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(E-2,3-diphenylpropenamide)HCID 20613747—

Reaction Steps

Prepared as free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-2,3-diphenylpropenoic acid; MS (ES+) 333 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683090B1
Source datasetuspto-grants-2004_01
ORD IDord-288a78f2b4f94bf29873c7241cdab3ec
Source noteuspto-grants-2004_01