HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-Methylcinnamic acid → (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(E-2-methyl-3-phenylpropenamide)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha-Methylcinnamic acid | HCID 637817 | — |
| Reactant | (R)-(+)-3-Aminoquinuclidine Dihydrochloride | HCID 12494972 | — |
| Product | (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)(E-2-methyl-3-phenylpropenamide) | HCID 20613749 | — |
Reaction Steps
Prepared as free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-2-methyl-3-phenylpropenoic acid; MS (ES+) 271 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683090B1 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-713c544b5aed4944943cf80d81728db1 |
| Source note | uspto-grants-2004_01 |