HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Methoxycinnamic Acid → (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)[E-3-(3-methoxyphenyl)propenamide]
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Methoxycinnamic Acid | HCID 637668 | — |
| Edukt | (R)-(+)-3-Aminoquinuclidine Dihydrochloride | HCID 12494972 | — |
| Produkt | (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)[E-3-(3-methoxyphenyl)propenamide] | HCID 20613759 | — |
Reaktionsschritte
Prepared as a free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-3-(3-methoxyphenyl)propenoic acid; the compound was purified by chromatography on silica gel using ammoniated methanol/chloroform mixtures as the eluent; MS (ES+) 287 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06683090B1 |
| Quelldatensatz | uspto-grants-2004_01 |
| ORD ID | ord-6bdaea84470c425c8d52e687fb4996f6 |
| Quellennotiz | uspto-grants-2004_01 |