HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorocinnamic acid → (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)[E-3-(2-chlorophenyl)propenamide]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorocinnamic acid | HCID 700642 | — |
| Reactant | (R)-(+)-3-Aminoquinuclidine Dihydrochloride | HCID 12494972 | — |
| Product | (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)[E-3-(2-chlorophenyl)propenamide] | HCID 20613748 | — |
Reaction Steps
Prepared as a free base by a method analogous to that described in Example 1 from (R)-1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-3-(2-chlorophenyl)propenoic acid; MS (ES+) 291 and 293 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683090B1 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-9d31496f4536400aacda549688fdbb65 |
| Source note | uspto-grants-2004_01 |