Quinuclidine, 3-amino-, dihydrochloride → HCID 10293236, compound

HRID 1840906Notes

Reaction equation

HRID 1840906 reaction equation
Cl.Cl.[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[CH:5]([NH2:11])[CH2:4]2.[I:12][C:13]1[CH:18]=[CH:17][C:16](/[CH:19]=[CH:20]/[C:21](O)=[O:22])=[CH:15][CH:14]=1>>[N:3]12[CH2:10][CH2:9][CH:6]([CH2:7][CH2:8]1)[CH:5]([NH:11][C:21](=[O:22])/[CH:20]=[CH:19]/[C:16]1[CH:17]=[CH:18][C:13]([I:12])=[CH:14][CH:15]=1)[CH2:4]2

Participants

3

Reactant 2

HCID 197853Quinuclidine, 3-amino-, dihydrochlorideHCID 5871757HCID 5871757, compound

Product 1

HCID 10293236HCID 10293236, compound

Procedure

Prepared as a free base by a method analogous to that described in Example 1 from racemic 1-azabicyclo[2.2.2]oct-3-ylamine dihydrochloride and E-3-(4-iodophenyl)propenoic acid; MS (ES+) 357 (MH+).

Workup

  1. customPrepared as a free base by a method analogous to

Sources & evidence

ORD record
ord-4d4e4d485de14018a736a40bbc65e8d1
Source dataset
uspto-grants-2004_01
Patent number
US06683090B1

Reaction notes

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