HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22312692, compound → HCID 86584978, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22312692 | HCID 22312692 | — |
| Reactant | HCID 23552768 | HCID 23552768 | — |
| Product | HCID 86584978 | HCID 86584978 | — |
Reaction Steps
Following General Procedure I above using cyclopentyl-α-hydroxyacetic acid (Example P) and 3-(L-alaninyl)-amino-2,4-dioxo-1,5-bis-(cyclopropylmethyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine hydrochloride (Example 8-U), the title compound was prepared as a white foam. Purification was by L.C. 2000 eluting with CH2Cl2/EtOAc (1:1 gradient to 1:2) then flash chromatography eluting with 2:1 EtOAc/CH2Cl2. Rf=0.47 and 0.37 (CH2Cl2/EtOAc, 1:2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683075B1 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-2f59ca0dc2214322a4b3d79fa2b55166 |
| Source note | uspto-grants-2004_01 |