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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1841159Generated: November 4, 2026

3-(Trifluoromethyl)benzeneacetic acid → 2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/1841159

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzeneacetic acidHCID 67695—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(3-trifluoromethylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 15481772—

Reaction Steps

Following General Procedure BI above and using 3-trifluoromethyl-phenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683075B1
Source datasetuspto-grants-2004_01
ORD IDord-eb513ae9593c4bc180f6e1a7ad8796d8
Source noteuspto-grants-2004_01