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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1841167Generated: November 3, 2026

2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → N-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/1841167

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Methyl-1,2-oxazol-5-yl)acetic acidHCID 4195532—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl EsterHCID 15481782—

Reaction Steps

Following General Procedure BI above, and using (3-methyl-isoxazol-5-yl)acetic acid (CAS #19668-85-0) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683075B1
Source datasetuspto-grants-2004_01
ORD IDord-6660ce6e917b4dc183cc127245c1e714
Source noteuspto-grants-2004_01