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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1841168Generated: November 3, 2026

2-methylpropyl (2S)-2-aminopropanoate → N-[(3-phenyl-1,2,4thiadiazol-5yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/1841168

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
Reactant2-(3-Phenyl-1,2,4-thiadiazol-5-yl)acetic acidHCID 22492184—
ProductN-[(3-phenyl-1,2,4thiadiazol-5yl)acetyl]alanine Iso-butyl EsterHCID 22894976—

Reaction Steps

Following General Procedure BI above, and using (3-phenyl-1,2,4-thiadiazol-5-yl)acetic acid (CAS #90771-06-5) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683075B1
Source datasetuspto-grants-2004_01
ORD IDord-2edff15e41e249399c7adf8ed07a9fe8
Source noteuspto-grants-2004_01