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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1841203Generated: October 26, 2026

2-(4-Chloro-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 3-(4-Chloro-3-methyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine Hydrochloride

https://huagongshe.com/reaction/1841203

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Chloro-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 3767641—
Reactant3-Bromo-5-(2-methyl-imidazol-1-ylmethyl)-pyridineHCID 23444965—
Product3-(4-Chloro-3-methyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine HydrochlorideHCID 23445052—

Reaction Steps

The title compound, MS: m/e=298.3 (M+H+) was obtained as a white solid (73% yield) by the reaction of 3-bromo-5-(2-methyl-imidazol-1-yl-methyl)-pyridine with 2-(4-chloro-3-methyl-phenyl)-4,4,5,5-tetramethyl[1,3,2]-dioxaborolane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683097B2
Source datasetuspto-grants-2004_01
ORD IDord-5677ef9aa91d4002955b4fafde724450
Source noteuspto-grants-2004_01