Thionyl Chloride → HCID 23444948, compound

HRID 1841228Notes

Reaction equation

HRID 1841228 reaction equation
[ClH:1].[CH3:2][C:3]1[CH:4]=[C:5]([C:10]2[CH:11]=[C:12]([CH2:17]O)[C:13]([CH3:16])=[N:14][CH:15]=2)[CH:6]=[CH:7][C:8]=1[CH3:9].S(Cl)([Cl:21])=O>>[ClH:21].[Cl:1][CH2:17][C:12]1[C:13]([CH3:16])=[N:14][CH:15]=[C:10]([C:5]2[CH:6]=[CH:7][C:8]([CH3:9])=[C:3]([CH3:2])[CH:4]=2)[CH:11]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 23445057HCID 23445057, compound

Product 1

HCID 23444948HCID 23444948, compound

Procedure

The title compound, MS: m/e=245.1 (M+) was obtained as a yellow solid (98% yield) by the reaction of [5-(3,4-dimethyl-phenyl)-2-methyl-pyridin-3-yl]-methanol hydrochloride (1:1) with thionyl chloride at 20° C. for 1 h then 2 h at reflux.

Sources & evidence

ORD record
ord-25b5e61e736f41f18986b6b75fc45f77
Source dataset
uspto-grants-2004_01
Patent number
US06683097B2

Reaction notes

Loading…