HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 5-Indanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 85654274 | HCID 85654274 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-Indanol | HCID 15118 | — |
| Product | Trifluoromethanesulfonic anhydride | HCID 67749 | — |
Reaction Steps
The title compound, MS: m/e=244.1 (M+) was obtained as a light yellow oil (96% yield) using trifluoro-methanesulfonic acid indan-5-yl ester obtained in turn from indan-5-ol by treatment with trifluoro-methanesulfonic anhydride, DMAP and triethylamine in CH2Cl2 at −70° C. to 20° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683097B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-38f37f138e54491094872909153f287b |
| Source note | uspto-grants-2004_01 |