HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 69038871, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 3-Aminoquinoline | HCID 11375 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | Ethyl nitroacetate | HCID 69379 | — |
| Catalyst | Iron | HCID 23925 | — |
| Product | HCID 69038871 | HCID 69038871 | — |
Reaction Steps
Following the general method described in example 384, 3-aminoquinoline was reacted with triethyl orthoformate, ethyl nitroacetate and acetic acid followed by treatment with triethyl orthoformate, iron and acetic acid. After workup and chromatography the title compound was obtained as a beige crystalline solid. Mp. 161-162° C. (AcOEt), MS: m/e=268 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06683097B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-f33af38b6b5b42acb0ff721f25435167 |
| Source note | uspto-grants-2004_01 |